Self-expandable Metallic Stent for Obstructive Colorectal Cancer in Our Hospital: Evaluation of Short-term Benefit / 日本農村医学会雑誌

Purpose: The self-expandable metallic stent (SEMS) for colorectal obstruction became covered by national health insurance in January 2012, and it has since become a standard treatment. Here we report the utility of SEMS for colorectal obstruction in our department. 　　Patients and Methods: We retrospectively reviewed 65 patients who underwent SEMS placement for colorectal obstruction in our department from May 2013 to December 2018. We examined age, sex, etiology of colorectal stenosis, purpose of stenting, and tumor location. 　　Results: The technical success rate was 98.5% (64/65) and the clinical success rate was 93.8% (61/65). Technical failure occurred in 1 case because the guidewire could not pass the stenosis. Adverse event rates were 1.6% within 7 days and 4.7% after 7 days. 　　Conclusion: SEMS placement had a high technical success rate and few adverse events. Clearly SEMS placement is a minimally invasive procedure that is effective for improving QOL. The safety and effectiveness of this procedure appeared to be excellent.

Improving Outcomes in Right Atrial Isomerism / 日本心臓血管外科学会雑誌

Surgery for right atrial isomerism usually has a poor outcome because of complex congenital cardiac malformations. Here we rearn the outcomes of all 71 consecutive patients with right atrial isomerism whom we treated from their initial operation at Shizuoka Children's Hospital between January 1987 and October 2006. We categorized 34 patients treated between 1987 and 1996 as the ‘early’ group, and 37 patients between 1997 and 2006 as the ‘late’ group. The early group was more commonly associated with pulmonary stenosis (<i>p</i>=0.010), and the late group was more commonly associated with neonatal status (<i>p</i>=0.010), body weight less than 3.0kg (<i>p</i>=0.037), and pulmonary atresia (<i>p</i>=0.013). All 71 patients were scheduled for single ventricular repair. Survival in the early group was 52.9% at 1 year, and 32.4% at 5 years, and this poor outcome was related to 2 factors; cardiac dysfunction from volume loading and inappropriate lung perfusion area for Fontan completion. We therefore changed our surgical strategy in the late group as follows: earlier right heart bypass operation and aggressive atrioventricular valvoplasty to prevent volume overloading, and central pulmonary artery (PA) strategy (central PA plasty and blood flow source anastomosed to the central PA) and improvement of anastomosis of total anomalous pulmonary venous connection (TAPVC) to preserve appropriate lung perfusion area. If severe unbalanced pulmonary blood flow occurred, it was treated with a novel surgical approach consisting of ‘intrapulmonary-artery septation’. Survival in the late group was 66.8% at 1 year, and 53.1% at 5 years, which was better than the early group, but not with statistical significance (<i>p</i>=0.102). Univariate analysis identified significant risk factors for mortality as neonatal status (<i>p</i>=0.036), extracardiac TAPVC (<i>p</i>=0.049), and preoperative pulmonary vein obstruction (PVO) (<i>p</i>=0.001) in the early group, and mixed TAPVC (<i>p</i>=0.001) in the late group. Multivariate analysis identified preoperative PVO (<i>p</i>=0.038) in the early group, and mixed TAPVC (<i>p</i>=0.007) in the late group as significant risk factors for mortality. Outcome is improving with our current strategy of preventing volume overloading and preserving an appropriate lung perfusion area, even in the late group with more severe cases, and neonatal status, extracardiac TAPVC, and preoperative PVO are no longer risk factors for mortality, but mixed type TAPVC remains a serious problem and is associated with high mortality.

A Case of Total Right Heart Bypass Operation for Polysplenia with Diffuse Bilateral Pulmonary Arteriovenous Fistula and Left Pulmonary Vein Obstruction by Anterior Translocation of the Hemiazygos Vein and Direct Anastomosis of the Hemiazygos Vein to the H / 日本心臓血管外科学会雑誌

Diffuse bilateral pulmonary arteriovenous fistula (PAVF) developed in a 19-month-old girl with polysplenia, single atrium, single right ventricle, left superior vena cava and interrupted inferior vena cava (IVC) after total cavopulmonary shunt (TCPS) operation. In addition, left pulmonary vein obstruction (PVO) by compression between the dilated hemiazygos vein and the atrium was identified. We performed total right heart bypass operation with anterior translocation of the hemiazygos vein for release of PVO and direct anastomosis of the hemiazygos vein to the hepatic vein to divert hepatic venous flow to the bilateral pulmonary circulation. Follow-up cardiac catheterization 9 months later showed disappearance of PAVF and no stenotic region. The merits of this operation are: 1) to provide balanced distribution of hepatic venous flow through the hemiazygos vein to the pulmonary circulation, 2) to release the PVO caused by the dilated hemiazygos vein, and 3) to allow for potential growth. This operation can be performed to Fontan candidates with interrupted IVC.